Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.48 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.48 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.40 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | HBB | P68871 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10656588 | 0.82 | LMNA (0.52) | LMNASMN1; SMN2CYP3A4CYP2D6MAPK3 | |
| SCHEMBL5352507 | 0.81 | MAPK1 (0.38) | LMNA | |
| SCHEMBL25600799 | 0.78 | LMNA (0.46) | LMNASMN1; SMN2CYP3A4CYP2D6MAPK3 | |
| Acetic Acid SCHEMBL28372215 | 0.77 | LMNA (0.48) | LMNASMN1; SMN2CYP3A4CYP2D6MAPK3 | |
| SCHEMBL7915827 | 0.75 | LMNA (0.49) | LMNASMN1; SMN2CYP3A4CYP2D6MAPK3 | |
| SCHEMBL11739898 | 0.75 | LMNA (0.49) | LMNASMN1; SMN2CYP3A4CYP2D6MAPK3 | |
| SCHEMBL11024545 | 0.72 | LMNA (0.61) | LMNASMN1; SMN2CYP3A4CYP2D6MAPK3 | |
| SCHEMBL11092234 | 0.72 | LMNA (0.57) | LMNASMN1; SMN2CYP3A4CYP2D6MAPK3 | |
| SCHEMBL10459087 | 0.72 | ASAH1 (0.72) | LMNASMN1; SMN2CYP3A4CYP2D6MAPK3 | |
| SCHEMBL26034526 | 0.72 | SQOR (0.46) | LMNASMN1; SMN2CYP3A4CYP2D6MAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506979-B1 | ORGANIC POLYMER COMPOUND AND PRODUCTION THEREOF | KUZUYA MASAYUKI (JP) | 2001-07-11 | — | — | EP | disclosed |
| US-5889078-A | HOMO OR COPOLYMERISING ACRYLIC OR METHACRYLIC ACID DERIVATIVE FORMED BY REACTING ACID DERIVATIVE WITH DRUGS-ACETAMINOPHEN, NICOTINAMIDE, FLUOROURACIL, AMPHOTERICIN B, METHYLDOPA AND CEPHALEXIN BY GRINIDNG, RUBBING AND HIGH SPEED VIBRATION | EISAI CO., LTD. (JP) | 1999-03-30 | — | — | US | disclosed |
| US-5821281-A | COPOLYMERIZING ACRYLIC OR METHACRYLIC ACID DERIVATIVE HAVING DRUG BONDED THERETO WITH ADDITIONAL ACRYLIC MONOMER IN SOLID PHASE IN ABSENCE OF SOLVENT UNDER MECHANICAL FORCE | EISAI CO., LTD. (JP) | 1998-10-13 | — | — | US | disclosed |
| EP-0506979-A1 | ORGANIC POLYMER COMPOUND AND PRODUCTION THEREOF | Eisai Co., Ltd. (JP) | 1992-10-07 | — | — | EP | disclosed |
| US-5053228-A | POLYMERIC TEMPERATURE SENSITIVE DRUG CARRIER | W. R. GRACE & CO.-CONN. (US) | 1991-10-01 | — | — | US | disclosed |
| EP-0413281-A2 | Drug carrier | W.R. Grace & Co.-Conn. (US) | 1991-02-20 | — | — | EP | disclosed |