SCHEMBL776505

SCHEMBL776505

Cc1ccc(S(=O)(=O)O)c(C(F)F)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.36
ALDH1A1 P00352 3/20 0.36
KMT2A Q03164 3/20 0.36
MAPT P10636 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
KDM4E B2RXH2 2/20 0.36
MEN1 O00255 1/20 0.36
POLB P06746 1/20 0.36
RECQL P46063 1/20 0.36
CASP6 P55212 1/20 0.36
ELAVL1 Q15717 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
LMNA P02545 5/20 0.36
HSD17B10 Q99714 1/20 0.36
TP53 P04637 1/20 0.35
MPL P40238 1/20 0.35
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
HPGD P15428 2/20 0.33
MEP1B Q16820 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL242353 0.87 LMNA (0.36) GAAALDH1A1KMT2AMAPTL3MBTL1
SCHEMBL625780 0.86 GAA (0.35) GAAALDH1A1KMT2AMAPTL3MBTL1
SCHEMBL531432 0.83 LMNA (0.47) GAAALDH1A1KMT2AMAPTL3MBTL1
SCHEMBL30666645 0.83 LMNA (0.38) GAAALDH1A1KMT2AMAPTL3MBTL1
SCHEMBL9101570 0.83 LMNA (0.38) GAAALDH1A1KMT2AMAPTL3MBTL1
SCHEMBL30716899 0.83 LMNA (0.38) GAAALDH1A1KMT2AMAPTL3MBTL1
SCHEMBL30667146 0.83 LMNA (0.38) GAAALDH1A1KMT2AMAPTL3MBTL1
SCHEMBL3743829 0.83 RAPGEF4 (0.35) GAAALDH1A1KMT2AMAPTL3MBTL1
SCHEMBL9243134 0.82 MAPT (0.35) GAAALDH1A1KMT2AMAPTL3MBTL1
SCHEMBL8464278 0.81 LMNA (0.37) GAAALDH1A1KMT2AMAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021046347-A1 IMMUNOCONJUGATE SYNTHESIS METHOD BOLT BIOTHERAPEUTICS, INC. (US) 2021-03-11 WO disclosed
US-9343777-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-05-17 US disclosed
US-9252457-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-02-02 US disclosed
US-20120177988-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-07-12 US disclosed
US-20120070731-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-03-22 US disclosed
US-20090325065-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2009-12-31 US disclosed