Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.79 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.74 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.74 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.74 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.74 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.74 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.74 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.74 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.74 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.74 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.74 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.65 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.65 |
| ▸ | F13A1 | P00488 | 1/20 | 0.64 |
| ▸ | CA12 | O43570 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | CA9 | Q16790 | 1/20 | 0.63 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL166980 | 0.94 | L3MBTL1 (0.71) | L3MBTL1HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL2186352 | 0.94 | HDAC2 (0.72) | L3MBTL1HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL4074353 | 0.92 | HDAC3 (0.87) | L3MBTL1HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL2808337 | 0.91 | L3MBTL1 (0.67) | L3MBTL1HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL10095127 | 0.91 | L3MBTL1 (0.67) | L3MBTL1HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL13073412 | 0.90 | HDAC3 (0.78) | L3MBTL1HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL3825861 | 0.90 | HDAC3 (0.68) | L3MBTL1HDAC3HDAC1HDAC2HDAC10 | |
| Fenaclon SCHEMBL2109480 | 0.89 | HDAC3 (0.66) | L3MBTL1HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL1690856 | 0.89 | HPGD (0.71) | L3MBTL1HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL19721599 | 0.89 | HDAC3 (0.66) | L3MBTL1HDAC3HDAC1HDAC2HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098662-A2 | COADMINISTRATION OF ACAT AND MMP INHIBITORS FOR THE TREATMENT OF ATHEROSCLEROTIC LESIONS | WARNER-LAMBERT COMPANY (US) | 2001-05-16 | — | — | EP | claimed |
| WO-2000004892-A2 | COADMINISTRATION OF ACAT AND MMP INHIBITORS FOR THE TREATMENT OF ATHEROSCLEROTIC LESIONS | WARNER-LAMBERT COMPANY (US) | 2000-02-03 | — | — | WO | claimed |