Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.87 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.87 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.87 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.87 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.87 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.87 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.87 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.87 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.87 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.87 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | F13A1 | P00488 | 1/20 | 0.69 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.66 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440269 | 0.95 | LMNA (0.82) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL13073412 | 0.94 | HDAC3 (0.78) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL25840478 | 0.93 | HDAC3 (0.77) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL15598132 | 0.93 | HDAC1 (1.00) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL17117356 | 0.93 | HDAC1 (0.79) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL7765076 | 0.92 | L3MBTL1 (0.79) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL25841202 | 0.92 | HDAC3 (0.74) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL7280705 | 0.91 | HDAC3 (0.77) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL2186352 | 0.90 | HDAC2 (0.72) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL6609568 | 0.90 | HDAC1 (0.72) | HDAC3HDAC1HDAC2HDAC10HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745010-B1 | SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2009-08-05 | — | — | EP | claimed |