Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 4/20 | 0.45 |
| ▸ | MMP3 | P08254 | 3/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP8 | P22894 | 2/20 | 0.43 |
| ▸ | MMP7 | P09237 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.37 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7763922 | 0.86 | HPGD (0.43) | MEN1KMT2AHPGDALOX5NPC1 | |
| SCHEMBL7976210 | 0.86 | HPGD (0.43) | MEN1KMT2AHPGDALOX5NPC1 | |
| SCHEMBL9329102 | 0.81 | MMP1 (0.52) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL9709399 | 0.80 | MMP1 (0.50) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL15650703 | 0.78 | MMP1 (0.50) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL15650705 | 0.78 | MMP1 (0.50) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL56847 | 0.75 | EPOR (0.52) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL55669 | 0.75 | EPOR (0.52) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL55668 | 0.75 | EPOR (0.52) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL5021056 | 0.75 | MMP1 (0.48) | MMP1MMP3MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6239308-B1 | REARRANGEMENT IN PRESENCE OF A BASE A KETO-HEMIMERCAPTAL CARBOXYLATE | AJINOMOTO CO., INC. (JP) | 2001-05-29 | — | — | US | disclosed |
| EP-0767168-B1 | Alpha-acyloxy-beta-aminothiolcarboxylic esters and method and intermediates for their production | AJINOMOTO KK (JP) | 2001-05-23 | — | — | EP | disclosed |
| US-6169200-B1 | ALPHA-ACYLOXY-THIOESTERS USEFUL ENZYME INHIBITORS, SUCH AS HIV PROTEASE AND RENIN | AJINOMOTO CO., INC. (JP) | 2001-01-02 | — | — | US | disclosed |
| US-5883284-A | Method for producing α-hydroxy-β-aminocarboxylic acids | AJINOMOTO CO., INC. (JP) | 1999-03-16 | — | — | US | disclosed |
| US-5817859-A | CHEMICAL INTERMEDIATE FOR ENZYME INHIBITORS, ANTICARCER AGENTS | AJINOMOTO CO., INC. (JP) | 1998-10-06 | — | — | US | disclosed |
| US-5705671-A | REARRANGEMENTS TO FORM SULFOXY ESTER AMIDES FROM KETO HEMIMERCAPTAL CARBOXYLATE, REACTING N-PROTECTED ALPHA AMINO CARBOXYLATE WITH SULFOXIDE AND AMINO KETOSULFOXIDE | AJINOMOTO CO., INC. (JP) | 1998-01-06 | — | — | US | disclosed |
| EP-0767168-A2 | Alpha-hydroxy-beta-aminothiolcarboxylic esters and method and intermediates for their production | Ajinomoto Co., Inc. (JP) | 1997-04-09 | — | — | EP | disclosed |