Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7763922 | 1.00 | HPGD (0.43) | HPGDALDH1A1MAPTALPLPOLB | |
| SCHEMBL7765570 | 0.86 | MMP1 (0.45) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7969873 | 0.79 | HPGD (0.43) | HPGDALDH1A1MAPTALPLPOLB | |
| SCHEMBL7959811 | 0.79 | HPGD (0.40) | HPGDALDH1A1MAPTALPLPOLB | |
| SCHEMBL5169748 | 0.78 | ALDH1A1 (0.46) | HPGDALDH1A1MAPTSIGMAR1MEN1 | |
| SCHEMBL5170328 | 0.78 | ALDH1A1 (0.46) | HPGDALDH1A1MAPTSIGMAR1MEN1 | |
| SCHEMBL5169742 | 0.78 | ALDH1A1 (0.46) | HPGDALDH1A1MAPTSIGMAR1MEN1 | |
| SCHEMBL6330627 | 0.78 | CPA1 (0.45) | HPGDALDH1A1MAPTSIGMAR1MEN1 | |
| SCHEMBL27686290 | 0.78 | CPA1 (0.45) | HPGDALDH1A1MAPTSIGMAR1MEN1 | |
| SCHEMBL9328442 | 0.78 | HPGD (0.50) | HPGDALDH1A1MAPTSIGMAR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281379-B1 | HALOGENATING G-AMINO-B-KETO SULFOXIDE; REACTING WITH ACID AND ALCOHOL; FORMING B-AMINO-A-HYDROXY ACID COMPOUNDS | KANEKA CORPORATION (JP) | 2001-08-28 | — | — | US | disclosed |
| EP-1055664-A1 | Process for producing norstatin derivatives | KANEKA CORPORATION (JP) | 2000-11-29 | — | — | EP | disclosed |