Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 4/20 | 0.50 |
| ▸ | MMP3 | P08254 | 3/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.48 |
| ▸ | MMP9 | P14780 | 2/20 | 0.48 |
| ▸ | MMP8 | P22894 | 2/20 | 0.48 |
| ▸ | MMP7 | P09237 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709725 | 0.87 | HPGD (0.48) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL9329102 | 0.83 | MMP1 (0.52) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL9329188 | 0.82 | TP53 (0.47) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL55669 | 0.81 | EPOR (0.52) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL56847 | 0.81 | EPOR (0.52) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL55668 | 0.81 | EPOR (0.52) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL15650703 | 0.80 | MMP1 (0.50) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL15650705 | 0.80 | MMP1 (0.50) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL7765570 | 0.80 | MMP1 (0.45) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL5021056 | 0.77 | MMP1 (0.48) | MMP1MMP3MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992010510-A1 | DITHIOLANO- AND DITHIANOGLYCIN-CONTAINING RENIN-INHIBITING PEPTIDES, PROCESS FOR PRODUCING THE SAME AND THEIR USE IN MEDICAMENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-25 | — | — | WO | disclosed |