Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 5/20 | 0.51 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.49 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.49 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7762771 | 1.00 | MMP8 (0.51) | MMP8ITGB1ITGA4ITGB7KMT2A | |
| SCHEMBL7761865 | 0.93 | L3MBTL1 (0.53) | MMP8ITGB1ITGA4ITGB7MMP1 | |
| SCHEMBL7765671 | 0.90 | MMP1 (0.56) | MMP8ITGB1ITGA4ITGB7MMP1 | |
| SCHEMBL7202935 | 0.87 | MMP1 (0.53) | MMP8ITGB1ITGA4ITGB7MMP1 | |
| SCHEMBL7406067 | 0.86 | ITGB1 (0.61) | MMP8ITGB1ITGA4ITGB7KMT2A | |
| SCHEMBL7763984 | 0.85 | MMP1 (0.55) | ITGB1ITGA4ITGB7MMP1 | |
| SCHEMBL7762748 | 0.85 | HDAC3 (0.49) | KMT2A | |
| SCHEMBL7761903 | 0.84 | ITGB1 (0.52) | MMP8ITGB1ITGA4ITGB7MMP1 | |
| SCHEMBL9229825 | 0.83 | TACR1 (0.54) | ITGB1ITGA4ITGB7KMT2AL3MBTL1 | |
| SCHEMBL7406177 | 0.83 | ITGB1 (0.48) | MMP8ITGB1ITGA4ITGB7MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808839-B1 | EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF, AND DRUGS CONTAINING THE SAME | TAIHO PHARMACEUTICAL CO LTD (JP) | 2001-05-23 | — | — | EP | disclosed |
| EP-0808839-A1 | EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF, AND DRUGS CONTAINING THE SAME | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1997-11-26 | — | — | EP | disclosed |