Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 6/20 | 0.57 |
| ▸ | CTSL | P07711 | 4/20 | 0.48 |
| ▸ | CTSB | P07858 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CTSG | P08311 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7765666 | 0.88 | CAPN1 (0.59) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL7761860 | 0.87 | CAPN1 (0.58) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL7762766 | 0.86 | CTSL (0.60) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL7765662 | 0.86 | CTSL (0.60) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL7763979 | 0.85 | CAPN1 (0.77) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL7202933 | 0.85 | CAPN1 (0.64) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL7402596 | 0.84 | CAPN1 (0.55) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL7355755 | 0.84 | L3MBTL1 (0.42) | CAPN1CTSLCTSBL3MBTL1CTSS | |
| SCHEMBL11667610 | 0.84 | CAPN1 (0.61) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL7406064 | 0.84 | CAPN1 (0.61) | CAPN1CTSLCTSBLMNACTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556853-A | THIOL PROTEASE INHIBITORS, TREATMENT OF OSTEOPOROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0655447-A1 | Epoxysuccinic acid derivatives | Takeda Chemical Industries, Ltd. (JP) | 1995-05-31 | — | — | EP | disclosed |