SCHEMBL7765738

SCHEMBL7765738

Cc1ccc(S(N)(=O)=O)c(C)c1Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
GAA P10253 1/20 0.45
LMNA P02545 3/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CYP2C9 P11712 3/20 0.40
CYP2D6 P10635 2/20 0.40
PDIA6 Q15084 1/20 0.40
CA1 P00915 10/20 0.39
CA2 P00918 10/20 0.39
CA4 P22748 4/20 0.39
CA12 O43570 9/20 0.38
CA9 Q16790 9/20 0.38
CA6 P23280 5/20 0.38
CA5A P35218 5/20 0.38
CA7 P43166 5/20 0.38
CA5B Q9Y2D0 5/20 0.38
CA14 Q9ULX7 3/20 0.38
CA13 Q8N1Q1 2/20 0.38
PTGES2 Q9H7Z7 2/20 0.38
CYP2C19 P33261 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3091342 0.85 CA2 (0.45) ALDH1A1GAALMNAL3MBTL1CYP2C9
SCHEMBL31453875 0.81 TRPV4 (0.40) ALDH1A1GAAL3MBTL1CYP2C19
SCHEMBL9343399 0.81 L3MBTL1 (0.44) ALDH1A1GAAL3MBTL1
SCHEMBL31453874 0.81 L3MBTL1 (0.44) ALDH1A1GAAL3MBTL1
SCHEMBL701462 0.80 ALDH1A1 (0.55) ALDH1A1GAALMNAL3MBTL1CYP2C9
SCHEMBL23043571 0.79 ALDH1A1 (0.52) ALDH1A1GAALMNAL3MBTL1CYP2C9
SCHEMBL9828277 0.79 MEN1 (0.44) ALDH1A1GAALMNAL3MBTL1KDM4E
Hydrochloric Acid SCHEMBL8306778 0.78 ALDH1A1 (0.53) ALDH1A1GAALMNAL3MBTL1PDIA6
Hydrochloric Acid SCHEMBL6021662 0.78 ALDH1A1 (0.53) ALDH1A1GAALMNAL3MBTL1PDIA6
SCHEMBL5935086 0.77 ALDH1A1 (0.51) ALDH1A1GAALMNAL3MBTL1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102361837-A Process for producing conjugated aromatic compound SUMITOMO CHEMICAL CO 2012-02-22 CN disclosed
EP-0945449-B1 Process for the preparation of saccharincarboxylic acid halides BASF AG (DE) 2001-05-23 EP disclosed
US-5981758-A Preparation of saccharincarbonyl halides BASF AKTIENGESELLSCHAFT (DE) 1999-11-09 US disclosed
EP-0945449-A1 Process for the preparation of saccharincarboxylic acid halides BASF AKTIENGESELLSCHAFT (DE) 1999-09-29 EP disclosed