Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 13/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.35 |
| ▸ | PKN1 | Q16512 | 2/20 | 0.35 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.35 |
| ▸ | PLK4 | O00444 | 1/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7759242 | 0.91 | PARP1 (0.39) | PARP1MGAMGAASIMGAM2 | |
| SCHEMBL6589391 | 0.76 | LMNA (0.46) | PARP1MGAMGAASIMGAM2 | |
| SCHEMBL6585330 | 0.71 | PARP1 (0.43) | PARP1 | |
| SCHEMBL7764171 | 0.71 | PARP1 (0.47) | PARP1MGAMGAASIMGAM2 | |
| SCHEMBL7763612 | 0.71 | PARP1 (0.41) | PARP1MGAMGAASIMGAM2 | |
| SCHEMBL6591702 | 0.71 | PARP1 (0.44) | PARP1MGAMGAASIMGAM2 | |
| SCHEMBL6585205 | 0.70 | PARP1 (0.42) | PARP1MGAMGAASIMGAM2 | |
| SCHEMBL6587560 | 0.70 | PARP1 (0.42) | PARP1MGAMGAASIMGAM2 | |
| SCHEMBL6590978 | 0.70 | PARP1 (0.42) | PARP1MGAMGAASIMGAM2 | |
| SCHEMBL6591546 | 0.70 | PARP1 (0.44) | PARP1CHEK2PKN1PKN2PLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001082877-A2 | USE OF PARP INHIBITORS IN COSMETIC PREPARATIONS | BASF AKTIENGESELLSCHAFT (DE) | 2001-11-08 | — | — | WO | disclosed |