SCHEMBL7765965

SCHEMBL7765965

COC(=O)NC(C([NH])=O)C(C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7765983 0.80 LMNA (0.39)
SCHEMBL19174545 0.80 SMN1; SMN2 (0.38) CA1CA2CA7
SCHEMBL3265337 0.80 ALDH1A1 (0.33) CA1CA2CA7
SCHEMBL14479851 0.80 CA2 (0.40) CA1CA2CA7
SCHEMBL192054 0.80 CA2 (0.40) CA1CA2CA7
SCHEMBL12661104 0.80 ALDH1A1 (0.33) CA1CA2CA7
SCHEMBL6418 0.80 CA2 (0.40) CA1CA2CA7
SCHEMBL3265209 0.80 ALDH1A1 (0.33) CA1CA2CA7
SCHEMBL7766049 0.79 CA1 (0.31) CA1CA2CA7
SCHEMBL7765969 0.78 CNR2 (0.35) CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0765879-B1 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests SANKYO CO (JP) 2001-02-14 EP disclosed
US-5861429-A MITICIDES AND ANTHELMINTICS SANKYO COMPANY, LIMITED (JP) 1999-01-19 US disclosed
EP-0765879-A1 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests SANKYO COMPANY LIMITED (JP) 1997-04-02 EP disclosed