Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | ACHE | P22303 | 8/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7769323 | 0.86 | EPHX1 (0.55) | EPHX1TSHRACHEMEN1KMT2A | |
| SCHEMBL7769387 | 0.85 | EPHX1 (0.59) | EPHX1TSHRACHEMEN1KMT2A | |
| SCHEMBL7770935 | 0.83 | EPHX1 (0.62) | EPHX1ACHE | |
| SCHEMBL7771583 | 0.83 | EPHX1 (0.62) | EPHX1ACHE | |
| SCHEMBL7769261 | 0.80 | ACHE (0.44) | ACHEKMT2A | |
| SCHEMBL3190326 | 0.79 | EPHX1 (0.61) | EPHX1TSHRACHEMEN1HSP90AA1 | |
| SCHEMBL7771523 | 0.79 | ALOX15 (0.40) | TSHRMEN1KMT2A | |
| SCHEMBL7765884 | 0.79 | TDP1 (0.55) | EPHX1MEN1KMT2ACA12 | |
| SCHEMBL5949703 | 0.78 | EPHX1 (0.50) | EPHX1TSHRACHEMEN1HSP90AA1 | |
| SCHEMBL205904 | 0.78 | EPHX1 (0.50) | EPHX1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |