Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | PPID | Q08752 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7767616 | 1.00 | LMNA (0.44) | LMNACA12CA9TSHRANPEP | |
| SCHEMBL7882654 | 1.00 | LMNA (0.44) | LMNACA12CA9TSHRANPEP | |
| SCHEMBL538340 | 0.83 | TSHR (0.54) | LMNACA12CA9TSHRSMN1; SMN2 | |
| SCHEMBL538339 | 0.83 | TSHR (0.54) | LMNACA12CA9TSHRSMN1; SMN2 | |
| SCHEMBL1694618 | 0.81 | CA12 (0.44) | LMNACA12CA9TSHRGAA | |
| SCHEMBL11032203 | 0.81 | CA12 (0.44) | LMNACA12CA9TSHRGAA | |
| SCHEMBL1694616 | 0.81 | CA12 (0.44) | LMNACA12CA9TSHRGAA | |
| SCHEMBL11130899 | 0.81 | TSHR (0.41) | LMNACA12CA9TSHRSMN1; SMN2 | |
| SCHEMBL7288159 | 0.81 | TSHR (0.41) | LMNACA12CA9TSHRSMN1; SMN2 | |
| SCHEMBL22873096 | 0.79 | CA12 (0.41) | LMNACA12CA9TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0759066-B1 | PROCESS FOR OBTAINING MICRO-ORGANISMS CONTAINING PEPTIDE AMIDASE, MICRO-ORGANISMS OBTAINED THEREWITH, PEPTIDE AMIDASES CONTAINED IN THEM AND USE THEREOF | DEGUSSA (DE) | 2001-06-27 | — | — | EP | disclosed |