SCHEMBL7766754

SCHEMBL7766754

CC1(C)Oc2c(F)cc(C(F)(F)F)cc2[C@H]2O[C@H]21

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9299207 0.75 CYP1A2 (0.37) IDO1
SCHEMBL7768331 0.75 CYP1A2 (0.37) IDO1
SCHEMBL9753193 0.72 TRPV1 (0.36) IDO1
SCHEMBL7874514 0.68 IDO1 (0.33) IDO1
SCHEMBL13951476 0.67 IDO1 (0.32) IDO1
SCHEMBL8071361 0.66 IDO1 (0.33) IDO1
SCHEMBL3945682 0.65 PGR (0.37) IDO1
SCHEMBL3945678 0.65 PGR (0.37) IDO1
SCHEMBL4032191 0.65 PGR (0.37) IDO1
SCHEMBL12961906 0.65 PGR (0.37) IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1109801-A1 SUBSTITUTED DIHYDROBENZOPYRANS USEFUL AS ANTIARRHYTHMIC AGENTS THE PROCTER & GAMBLE COMPANY (US) 2001-06-27 EP disclosed
WO-2000014084-A1 SUBSTITUTED DIHYDROBENZOPYRANS USEFUL AS ANTIARRHYTHMIC AGENTS THE PROCTER & GAMBLE COMPANY (US) 2000-03-16 WO disclosed