Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9299207 | 0.90 | CYP1A2 (0.37) | IDO1ABCB1CNR2 | |
| SCHEMBL7768331 | 0.90 | CYP1A2 (0.37) | IDO1ABCB1CNR2 | |
| SCHEMBL9581542 | 0.85 | ALDH1A1 (0.36) | IDO1ABCB1CNR2 | |
| SCHEMBL9582136 | 0.85 | ALDH1A1 (0.36) | IDO1ABCB1CNR2 | |
| SCHEMBL9582131 | 0.85 | ALDH1A1 (0.36) | IDO1ABCB1CNR2 | |
| SCHEMBL8136338 | 0.80 | — | — | |
| SCHEMBL9753193 | 0.78 | TRPV1 (0.36) | IDO1CNR2 | |
| SCHEMBL7870442 | 0.77 | KCNE1 (0.36) | — | |
| SCHEMBL6274078 | 0.76 | IDO1 (0.40) | IDO1ABCB1 | |
| SCHEMBL5868353 | 0.76 | IDO1 (0.40) | IDO1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571822-B1 | Diazabicycloalkene derivatives | DAIICHI SEIYAKU CO (JP) | 2001-08-16 | — | — | EP | disclosed |
| US-5418232-A | Hypotensive, increases renal blood flow | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1995-05-23 | — | — | US | disclosed |
| EP-0571822-A1 | Diazabicycloalkene derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1993-12-01 | — | — | EP | disclosed |
| WO-1990014346-A1 | BENZOPYRAN DERIVATIVES | BEECHAM GROUP PLC (GB) | 1990-11-29 | — | — | WO | disclosed |
| EP-0398665-A1 | Benzopyran derivatives | Beecham Group p.l.c. (GB) | 1990-11-22 | — | — | EP | disclosed |