Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | HTR2B | P41595 | 3/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | CYBB | P04839 | 1/20 | 0.32 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.32 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.32 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9299207 | 1.00 | CYP1A2 (0.37) | CYP1A2CYP2D6CNR2TERTKCNA5 | |
| SCHEMBL7874514 | 0.90 | IDO1 (0.33) | CNR2IDO1ABCB1 | |
| SCHEMBL9753193 | 0.88 | TRPV1 (0.36) | CNR2CHRNB2CHRNA4IDO1TRPV1 | |
| SCHEMBL9582136 | 0.86 | ALDH1A1 (0.36) | CNR2IDO1ABCB1 | |
| SCHEMBL9582131 | 0.86 | ALDH1A1 (0.36) | CNR2IDO1ABCB1 | |
| SCHEMBL9581542 | 0.86 | ALDH1A1 (0.36) | CNR2IDO1ABCB1 | |
| SCHEMBL8137939 | 0.79 | CYP1A2 (0.36) | CYP1A2CYP2D6TERTCHRNB2CHRNA4 | |
| SCHEMBL7870442 | 0.78 | KCNE1 (0.36) | CYP2D6BACE1TRPV1 | |
| SCHEMBL7821557 | 0.78 | SERPINE1 (0.40) | KCNA5 | |
| SCHEMBL5868357 | 0.78 | IDO1 (0.40) | IDO1HTR2CHTR2BABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109801-A1 | SUBSTITUTED DIHYDROBENZOPYRANS USEFUL AS ANTIARRHYTHMIC AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 2001-06-27 | — | — | EP | disclosed |
| WO-2000014084-A1 | SUBSTITUTED DIHYDROBENZOPYRANS USEFUL AS ANTIARRHYTHMIC AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 2000-03-16 | — | — | WO | disclosed |