Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7762182 | 0.83 | ACE (0.37) | POLBKMT2AMEN1 | |
| SCHEMBL7769337 | 0.76 | KMT2A (0.33) | KMT2A | |
| SCHEMBL7767499 | 0.71 | POLB (0.31) | POLB | |
| SCHEMBL7767497 | 0.64 | — | — | |
| SCHEMBL7765004 | 0.62 | KIF11 (0.33) | — | |
| SCHEMBL7767464 | 0.59 | TP53 (0.32) | KMT2A | |
| SCHEMBL7762192 | 0.57 | POLB (0.44) | POLBKMT2AMEN1 | |
| SCHEMBL8467419 | 0.56 | — | — | |
| SCHEMBL16722800 | 0.55 | — | — | |
| SCHEMBL9033457 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639566-B1 | CYCLIC COMPOUND | SANTEN PHARMACEUTICAL CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-5461158-A | Immunodeficiency and autoimmune diseases | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1995-10-24 | — | — | US | disclosed |
| EP-0639566-A1 | CYCLIC COMPOUND | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1995-02-22 | — | — | EP | disclosed |