Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9438251 | 0.83 | MMP8 (0.36) | ALDH1A1MMP8CYP3A4CYP2C19HSD17B10 | |
| SCHEMBL22490101 | 0.82 | MMP8 (0.42) | ALDH1A1MMP8CYP3A4CYP2C19HSD17B10 | |
| SCHEMBL9438324 | 0.82 | MMP8 (0.35) | ALDH1A1MMP8CYP3A4CYP2C19HSD17B10 | |
| SCHEMBL28291065 | 0.80 | MMP8 (0.43) | ALDH1A1MMP8CYP3A4CYP2C19HSD17B10 | |
| SCHEMBL14960625 | 0.80 | SMN1; SMN2 (0.38) | ALDH1A1MMP8HTTHPGD | |
| SCHEMBL2888741 | 0.80 | ALDH1A1 (0.40) | ALDH1A1MMP8HSD17B10LMNAGAA | |
| SCHEMBL20473354 | 0.80 | ALDH1A1 (0.40) | ALDH1A1MMP8HSD17B10LMNAGAA | |
| SCHEMBL6872825 | 0.79 | MMP8 (0.36) | ALDH1A1MMP8HSD17B10LMNAGAA | |
| SCHEMBL9408553 | 0.78 | HTT (0.40) | ALDH1A1MMP8HSD17B10LMNAGAA | |
| SCHEMBL9358305 | 0.78 | HTT (0.40) | ALDH1A1MMP8HSD17B10LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250098677-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION AG (CH) | 2025-03-27 | — | — | US | disclosed |
| US-12201113-B2 | Fungicidal compositions | SYNGENTA CROP PROTECTION AG (CH) | 2025-01-21 | — | — | US | disclosed |
| US-11744246-B2 | Preparation of mammalian oocyte for fertilization via a soluble human PH20 hyaluronidase polypeptide | SYNGENTA PARTICIPATIONS AG (CH) | 2023-09-05 | — | — | US | disclosed |
| CN-112770632-B | Fungicidal compositions | 先正达农作物保护股份公司 | 2022-12-27 | — | — | CN | disclosed |
| EP-3853207-B1 | MICROBIOCIDAL QUINOLINE CARBOXAMIDE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2022-10-19 | — | — | EP | disclosed |
| US-11440888-B2 | Microbiocidal quinoline carboxamide derivatives | SYNGENTA CROP PROTECTION AG (CH) | 2022-09-13 | — | — | US | disclosed |
| US-20220132845-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2022-05-05 | — | — | US | disclosed |
| US-20220030867-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION AG (CH) | 2022-02-03 | — | — | US | disclosed |
| US-11234437-B2 | Fungicidal compositions | SYNGENTA PARTICIPATIONS AG (CH) | 2022-02-01 | — | — | US | disclosed |
| US-20220015364-A1 | MICROBIOCIDAL QUINOLINE (THIO)CARBOXAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2022-01-20 | — | — | US | disclosed |
| EP-0768296-B1 | A method for making alpha, beta-unsaturated-beta-trifluoromethyl-carboxylates | ROHM & HAAS (US) | 2001-06-13 | — | — | EP | disclosed |
| EP-0432984-B1 | Carbamoyl derivatives | ZENECA LTD (GB) | 1998-03-04 | — | — | EP | disclosed |
| US-5679832-A | Method for making α,β-unsaturated-β-trifluoromethyl-carboxylates and related compounds | ROHM AND HAAS COMPANY (US) | 1997-10-21 | — | — | US | disclosed |
| EP-0768296-A1 | A method for making alpha, beta-unsaturated-beta-trifluoromethyl-carboxylates | ROHM AND HAAS COMPANY (US) | 1997-04-16 | — | — | EP | disclosed |
| EP-0489548-B1 | A process for the preparation of 2(R)-methyl-4,4,4-trifluorobutylamine, intermediates, and a process for the preparation of a derivative thereof | ZENECA LTD (GB) | 1994-12-14 | — | — | EP | disclosed |
| US-5334765-A | Intermediate for leukotriene antagonists | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-08-02 | — | — | US | disclosed |
| US-5286740-A | Leukotrine antagonists; antiinflammatory agnets, antiallergens, treating asthma | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-02-15 | — | — | US | disclosed |
| US-5274118-A | Process for preparing (2R)-methyl-4,4,4-trifluorobutylamine | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-12-28 | — | — | US | disclosed |
| EP-0489548-A1 | A process for the preparation of 2(R)-methyl-4,4,4-trifluorobutylamine, intermediates, and a process for the preparation of a derivative thereof | ZENECA LIMITED (GB) | 1992-06-10 | — | — | EP | disclosed |
| EP-0432984-A2 | Carbamoyl derivatives | ZENECA LIMITED (GB) | 1991-06-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220015364-A1 | MICROBIOCIDAL QUINOLINE (THIO)CARBOXAMIDE DERIVATIVES | IFNG, TLR1, IDO1 | ALDH1A1 1059/4885MMP8 2205/4885CYP3A4 473/4885 |
| US-12201113-B2 | Fungicidal compositions | CYP51A1, CYP4X1, CYP1B1 | ALDH1A1 477/4885MMP8 2373/4885CYP3A4 51/4885 |
| US-20250098677-A1 | FUNGICIDAL COMPOSITIONS | CYP51A1, CYP4X1, CYP1B1 | ALDH1A1 477/4885MMP8 2373/4885CYP3A4 51/4885 |
| US-20220132845-A1 | FUNGICIDAL COMPOSITIONS | CYP51A1, CYP4X1, CYP1B1 | ALDH1A1 477/4885MMP8 2373/4885CYP3A4 51/4885 |
| US-11234437-B2 | Fungicidal compositions | CYP1B1, CYP2F1, CYP3A43 | ALDH1A1 2827/4885MMP8 4053/4885CYP3A4 18/4885 |
| US-11440888-B2 | Microbiocidal quinoline carboxamide derivatives | IDO1, TLR1, TLR5 | ALDH1A1 1029/4885MMP8 1471/4885CYP3A4 656/4885 |
| US-11744246-B2 | Preparation of mammalian oocyte for fertilization via a soluble human PH20 hyaluronidase polypeptide | PHF20, FUCA1, ZP1 | ALDH1A1 1241/4885MMP8 1484/4885CYP3A4 2445/4885 |
| US-20220030867-A1 | FUNGICIDAL COMPOSITIONS | CYP1B1, CYP4B1, CYP3A43 | ALDH1A1 3481/4885MMP8 3269/4885CYP3A4 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.