Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 7/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7767283 | 1.00 | ALDH1A1 (0.44) | ALDH1A1POLBKDM4EVCAM1KDM1A | |
| SCHEMBL7765314 | 0.79 | TAAR1 (0.53) | ALDH1A1KDM4EHPGDMAPTKMT2A | |
| SCHEMBL7765310 | 0.79 | TAAR1 (0.53) | ALDH1A1KDM4EHPGDMAPTKMT2A | |
| SCHEMBL20856347 | 0.75 | ALDH1A1 (0.48) | ALDH1A1POLBKDM4EVCAM1KDM1A | |
| SCHEMBL7763034 | 0.73 | NPSR1 (0.47) | ALDH1A1POLBKDM4EVCAM1KDM1A | |
| SCHEMBL27311122 | 0.73 | VCAM1 (0.51) | ALDH1A1POLBKDM4EVCAM1KDM1A | |
| SCHEMBL213965 | 0.73 | VCAM1 (0.56) | ALDH1A1POLBKDM4EVCAM1KDM1A | |
| SCHEMBL29707970 | 0.73 | VCAM1 (0.56) | ALDH1A1POLBKDM4EVCAM1KDM1A | |
| SCHEMBL22615092 | 0.71 | ALDH1A1 (0.45) | ALDH1A1POLBKDM4EVCAM1KDM1A | |
| SCHEMBL7104418 | 0.71 | TAAR1 (0.49) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531702-B1 | Process for the manufacture of insecticidal, nematicidal and acaricidal 2-aryl-3-subst. -5-(trifluoromethyl)pyrrole compounds from N-(subst. benzyl)-2,2,2-trifluoroacetimidoyl chloride compounds | BASF AG (DE) | 2001-05-30 | — | — | EP | disclosed |
| EP-0531702-A1 | Process for the manufacture of insecticidal, nematicidal and acaricidal 2-aryl-3-substitued-5-(trifluoromethyl)pyrrole compounds from N-(substituted benzyl)-2,2,2-trifluoroacetimidoyl chloride compounds | AMERICAN CYANAMID COMPANY (US) | 1993-03-17 | — | — | EP | disclosed |
| US-5145986-A | Process for the manufacture of insecticidal, nematicidal and acaricidal 2-aryl-3-substituted-5-(trifluoromethyl)pyrrole compounds from N-(substituted benzyl)-2,2,2-trifluoro-acetimidoyl chloride compounds | AMERICAN CYANAMID COMPANY (US) | 1992-09-08 | — | — | US | disclosed |