Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 2/20 | 0.64 |
| ▸ | HTR1D | P28221 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | DRD4 | P21917 | 3/20 | 0.61 |
| ▸ | DRD2 | P14416 | 2/20 | 0.61 |
| ▸ | DRD3 | P35462 | 2/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2470398 | 0.81 | DRD2 (0.68) | HTR1BHTR1DKDM4EDRD4DRD2 | |
| SCHEMBL2468934 | 0.81 | HTR1B (0.67) | HTR1BHTR1DKDM4EALDH1A1DRD4 | |
| SCHEMBL26126465 | 0.80 | HTR1B (0.60) | HTR1BHTR1DKDM4EALDH1A1DRD4 | |
| SCHEMBL6557649 | 0.79 | MAOB (0.57) | KDM4EALDH1A1DRD4DRD2DRD3 | |
| Dimethylamine SCHEMBL6784757 | 0.79 | MAPT (0.59) | KDM4EALDH1A1DRD4DRD2DRD3 | |
| SCHEMBL12765155 | 0.79 | HTR1B (0.64) | HTR1BHTR1DKDM4EALDH1A1DRD4 | |
| Hydrochloric Acid SCHEMBL8042254 | 0.79 | DRD4 (0.77) | KDM4EALDH1A1DRD4DRD2DRD3 | |
| SCHEMBL5835871 | 0.79 | HTR1B (0.64) | HTR1BHTR1DKDM4EALDH1A1DRD4 | |
| Hydrochloric Acid SCHEMBL21595673 | 0.79 | DRD2 (0.66) | HTR1BHTR1DKDM4EDRD4DRD2 | |
| SCHEMBL12153434 | 0.79 | HTR1B (0.64) | HTR1BHTR1DKDM4EALDH1A1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7368449-B2 | 2-alkynyl- and 2-alkenyl-pyrazolo-[4,3-e]-1,2,4-triazolo-[1,5-c]-pyrimidine adenosine A2a receptor antagonists | SCHERING CORPORATION (US) | 2008-05-06 | — | — | US | disclosed |
| US-20040220194-A1 | 2-Alkynyl-and 2-alkenyl-pyrazolo-[4,3-e]-1,2,4-triazolo-[1,5-c]-pyrimidine adenosine A2a receptor antagonists | SCHERING CORPORATION | 2004-11-04 | — | — | US | disclosed |
| WO-2001091558-A1 | HERBICIDAL AGENTS BASED ON SUBSTITUTED CARBOXAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-12-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040220194-A1 | 2-Alkynyl-and 2-alkenyl-pyrazolo-[4,3-e]-1,2,4-triazolo-[1,5-c]-pyrimidine adenosine A2a receptor antagonists | ADORA2A, ADORA3, ADORA1 | HTR1B 33/4885HTR1D 35/4885KDM4E 4567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.