Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.35 |
| ▸ | GABRD | O14764 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.35 |
| ▸ | GABRE | P78334 | 2/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.35 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.35 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.35 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL466827 | 0.84 | — | — | |
| SCHEMBL18824851 | 0.84 | — | — | |
| Water SCHEMBL7767504 | 0.82 | ALDH1A1 (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Hydrochloric Acid SCHEMBL3507710 | 0.82 | ALDH1A1 (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Alanine SCHEMBL14688036 | 0.75 | GABRP (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Pivalate SCHEMBL11039116 | 0.74 | ALDH1A1 (0.40) | ALDH1A1KDM4ETSHRALOX15HMGCR | |
| Alanine SCHEMBL11163433 | 0.73 | GABRP (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Alanine SCHEMBL11163436 | 0.73 | GABRP (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL1370735 | 0.72 | MMP8 (0.46) | ALDH1A1KDM4ETSHRALOX15MMP8 | |
| SCHEMBL3391927 | 0.70 | SLC1A2 (0.38) | ALDH1A1MAPTPTGS1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842153-B1 | METHOD OF PREPARING NORBENZOMORPHANE AS AN INTERMEDIATE IN THE PREPARATION OF PHARMACEUTICALLY USEFUL BENZOMORPHANE DERIVATIVES, IN PARTICULAR (-)-(1R,5S,2\"R)-3'-HYDROXY-2-(2-METHOXYPROPYL)-5,9,9-TRIMETHYL-6,7-BENZOMORPHANE | BOEHRINGER INGELHEIM PHARMA (DE) | 2001-05-30 | — | — | EP | claimed |
| US-5945535-A | Method of preparing norbenzomorphanes | BOEHRINGER INGELHEIM KG (DE) | 1999-08-31 | — | — | US | claimed |