Sulfuric Acid

Sulfuric Acid

SCHEMBL7767532

CCN(O)c1ccc(N)c(C)c1.O=S(=O)(O)O

nearest known ligand 0.57

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100B P04271 1/20 0.57
ESR1 P03372 3/20 0.37
AR P10275 1/20 0.37
ESR2 Q92731 1/20 0.37
ALDH1A1 P00352 5/20 0.37
CYP3A4 P08684 4/20 0.37
TDP1 Q9NUW8 3/20 0.37
TSHR P16473 3/20 0.37
SKP2 Q13309 1/20 0.37
THRB P10828 3/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
HPGD P15428 2/20 0.35
GAA P10253 2/20 0.35
ALOX15 P16050 2/20 0.35
RECQL P46063 2/20 0.35
RAB9A P51151 2/20 0.35
KDM4E B2RXH2 1/20 0.35
MAPT P10636 1/20 0.35
PKM P14618 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8754635 0.92 S100B (0.67) S100BESR1ARESR2ALDH1A1
Sulfuric Acid SCHEMBL7955346 0.85 S100B (0.80) S100BALDH1A1CYP3A4TDP1TSHR
Methanesulfonamide SCHEMBL6897381 0.81 S100B (0.73) S100BESR1ARESR2ALDH1A1
Sulfuric Acid SCHEMBL9638822 0.80 S100B (0.49) S100BESR1ARESR2ALDH1A1
Sulfuric Acid SCHEMBL9566805 0.79 S100B (0.64) S100BESR1ARESR2ALDH1A1
Sulfuric Acid SCHEMBL10371487 0.79 S100B (0.64) S100BESR1ARESR2ALDH1A1
Sulfuric Acid SCHEMBL11125865 0.79 S100B (0.51) S100BESR1ARESR2ALDH1A1
Sulfuric Acid SCHEMBL10582678 0.79 S100B (0.64) S100BESR1ARESR2ALDH1A1
Sulfuric Acid SCHEMBL2931812 0.79 S100B (0.51) S100BESR1ARESR2ALDH1A1
Sulfuric Acid SCHEMBL2140481 0.79 S100B (0.64) S100BESR1ARESR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1109064-A1 Photographic processing element and image forming method by the use thereof KONICA CORPORATION (JP) 2001-06-20 EP disclosed
EP-0973064-A1 A color development process that results in high observed speeds EASTMAN KODAK COMPANY (US) 2000-01-19 EP disclosed
US-5541044-A USING A MALONDIAMIDE-TYPE YELLOW COUPLER AND A DEVELOPMENT INHIBITOR RELEASE (DIR) COMPOUND; SHARPNESS; STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1996-07-30 US disclosed
EP-0583004-A1 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1994-02-16 EP disclosed
EP-0513496-A1 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1992-11-19 EP disclosed