Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100B | P04271 | 1/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.44 |
| ▸ | GFER | P55789 | 6/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GRK2 | P25098 | 1/20 | 0.43 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methanesulfonamide SCHEMBL6897381 | 0.95 | S100B (0.73) | S100BALDH1A1L3MBTL1MEN1KMT2A | |
| Methanesulfonamide SCHEMBL793229 | 0.90 | S100B (0.80) | S100BALDH1A1L3MBTL1MEN1KMT2A | |
| Sulfuric Acid SCHEMBL2140481 | 0.90 | S100B (0.64) | S100BALDH1A1L3MBTL1MEN1KMT2A | |
| Sulfuric Acid SCHEMBL10371487 | 0.90 | S100B (0.64) | S100BALDH1A1L3MBTL1MEN1KMT2A | |
| Sulfuric Acid SCHEMBL9566805 | 0.90 | S100B (0.64) | S100BALDH1A1L3MBTL1MEN1KMT2A | |
| Sulfuric Acid SCHEMBL10945925 | 0.90 | S100B (0.64) | S100BALDH1A1L3MBTL1MEN1KMT2A | |
| Sulfuric Acid SCHEMBL10582678 | 0.90 | S100B (0.64) | S100BALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL34104 | 0.89 | S100B (1.00) | S100BALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL29350181 | 0.89 | S100B (1.00) | S100BALDH1A1L3MBTL1MEN1KMT2A | |
| Sulfuric Acid SCHEMBL9131658 | 0.88 | S100B (0.62) | S100BALDH1A1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265600-B1 | REACTING IMIDATE COMPOUND TO CONDENSATION REACTION IN NITROGEN ATOMOSPHERE IN PRESENCE OF BASE AND ACTIVATED METHYLENE COMPOUND TO FORM ACTIVATED PROPENE COMPOUND | EASTMAN KODAK COMPANY | 2001-07-24 | — | — | US | disclosed |
| US-5776669-A | Phenol substituted pyrazolo 1, 5-a benzimidazole couplers | EASTMAN KODAK COMPANY (US) | 1998-07-07 | — | — | US | disclosed |
| US-5460927-A | Reacting a propene compound with nucleophilic aniline derivatives; used in silver halide imaging system | EASTMAN KODAK COMPANY (US) | 1995-10-24 | — | — | US | disclosed |
| EP-0565531-B1 | ACTIVATED PROPENES AS COLOUR COUPLERS | KODAK LTD (GB) | 1995-09-06 | — | — | EP | disclosed |
| US-5443945-A | Magenta photographic couplers | EASTMAN KODAK COMPANY (US) | 1995-08-22 | — | — | US | disclosed |
| EP-0592509-B1 | ACTIVATED PROPENES AS COLOUR COUPLERS AND A METHOD FOR THEIR PRODUCTION | KODAK LTD (GB) | 1995-06-14 | — | — | EP | disclosed |
| EP-0358186-B1 | Photographic silver halide material and process | EASTMAN KODAK CO (US) | 1994-08-24 | — | — | EP | disclosed |
| EP-0594615-A1 | PHENOL SUBSTITUTED PYRAZOLO 1,5-a]BENZIMIDAZOLE COUPLERS | KODAK LIMITED (GB) | 1994-05-04 | — | — | EP | disclosed |
| EP-0592509-A1 | ACTIVATED PROPENES AS COLOUR COUPLERS AND A METHOD FOR THEIR PRODUCTION. | KODAK LTD (GB) | 1994-04-20 | — | — | EP | disclosed |
| EP-0213710-B1 | Method of processing silver halide color photographic material | KONISHIROKU PHOTO IND (JP) | 1994-01-12 | — | — | EP | disclosed |
| WO-1992000299-A1 | PHENOL SUBSTITUTED PYRAZOLO[1,5-a]BENZIMIDAZOLE COUPLERS | EASTMAN KODAK COMPANY (US) | 1992-01-09 | — | — | WO | disclosed |
| EP-0398750-A2 | Tone controlling compounds | EASTMAN KODAK COMPANY (US) | 1990-11-22 | — | — | EP | disclosed |
| EP-0358186-A2 | Photographic silver halide material and process | EASTMAN KODAK COMPANY (US) | 1990-03-14 | — | — | EP | disclosed |
| US-4908300-A | Developing imagewise exposed silver halide photographic material, maintaining dry thickness, bleach-fixing with organic acid ferric complex | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1990-03-13 | — | — | US | disclosed |
| US-4908304-A | Silver halide emulsion contains hydroxytetrazaindene compound and electron beam hardenable resin | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1990-03-13 | — | — | US | disclosed |
| US-4748105-A | Rapid bleach fixing of a silver halide color photographic light-sensitive material using an organic acid ferric complex | KONISIROKU PHOTO INDUSTRY COMPANY, LTD. (JP) | 1988-05-31 | — | — | US | disclosed |
| US-4707434-A | Color image forming method comprising processing with a bleach-fixing solution | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1987-11-17 | — | — | US | disclosed |
| EP-0213710-A2 | Method of processing silver halide color photographic material | KONICA CORPORATION (JP) | 1987-03-11 | — | — | EP | disclosed |
| EP-0175366-A2 | Silver halide photographic light-sensitive material | KONICA CORPORATION (JP) | 1986-03-26 | — | — | EP | disclosed |
| EP-0173540-A2 | Color image forming method | KONICA CORPORATION (JP) | 1986-03-05 | — | — | EP | disclosed |