Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7767882 | 0.88 | KDM4E (0.40) | KDM4ESMN1; SMN2ALDH1A1MAPK1RCE1 | |
| SCHEMBL7377097 | 0.87 | KDM4E (0.44) | KDM4ESMN1; SMN2ALDH1A1MAPK1RCE1 | |
| SCHEMBL7771929 | 0.86 | SCN5A (0.40) | KDM4ESMN1; SMN2ALDH1A1MAPK1RCE1 | |
| SCHEMBL7767896 | 0.85 | KDM4E (0.47) | KDM4ESMN1; SMN2ALDH1A1MAPK1RCE1 | |
| SCHEMBL7772054 | 0.84 | FPR1 (0.41) | KDM4ESMN1; SMN2ALDH1A1MAPK1RCE1 | |
| SCHEMBL7771927 | 0.81 | KDM4E (0.44) | KDM4ESMN1; SMN2ALDH1A1MAPK1RCE1 | |
| SCHEMBL7773814 | 0.80 | PTGDR2 (0.45) | KDM4EALDH1A1MAPK1RCE1NPC1 | |
| SCHEMBL7767885 | 0.78 | KDM4E (0.48) | KDM4ESMN1; SMN2ALDH1A1MAPK1RCE1 | |
| SCHEMBL7773564 | 0.77 | KDM4E (0.47) | KDM4ESMN1; SMN2ALDH1A1MAPK1RCE1 | |
| SCHEMBL7395782 | 0.77 | KDM4E (0.49) | KDM4ESMN1; SMN2ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6252082-B1 | CARDIOVASCUALR DISORDERS | SANOFI-SYNTHELABO (FR) | 2001-06-26 | — | — | US | disclosed |