Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 2/20 | 0.40 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.35 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7685431 | 1.00 | VNN1 (0.40) | VNN1PARP15PARP10PARP2OPRM1 | |
| SCHEMBL7685849 | 0.87 | F10 (0.39) | VNN1KCNH2 | |
| SCHEMBL7685436 | 0.78 | LSS (0.57) | VNN1OPRM1OPRK1KCNH2ACHE | |
| SCHEMBL7685430 | 0.78 | LSS (0.57) | VNN1OPRM1OPRK1KCNH2ACHE | |
| SCHEMBL6388670 | 0.75 | ADRA1D (0.44) | PARP15PARP10PARP2OPRM1OPRK1 | |
| SCHEMBL8035846 | 0.72 | LSS (0.43) | ACHE | |
| SCHEMBL7679275 | 0.72 | LSS (0.60) | RXFP1 | |
| SCHEMBL7771941 | 0.72 | LSS (0.60) | RXFP1 | |
| SCHEMBL8047384 | 0.69 | LSS (0.43) | ACHERXFP1 | |
| SCHEMBL8904544 | 0.69 | LSS (0.43) | ACHERXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778264-B1 | Tertiary amines having antimycotic and cholesterol lowering activity | HOFFMANN LA ROCHE (CH) | 2001-07-11 | — | — | EP | claimed |