SCHEMBL7768199

SCHEMBL7768199

CC(C)(N)c1cccc(F)c1Br

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.32
KCNN4 O15554 2/20 0.31
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24270237 0.79 CA2 (0.37) CA2KCNN4ACHE
SCHEMBL30018006 0.78 HSD11B1 (0.37) CA2KCNN4ACHE
SCHEMBL23886265 0.78 HSD11B1 (0.37) CA2KCNN4ACHE
SCHEMBL10873924 0.78 CES2 (0.32) KCNN4
SCHEMBL1239429 0.78 KCNN4 (0.42) KCNN4ACHE
SCHEMBL30017695 0.78 KCNN4 (0.42) KCNN4ACHE
SCHEMBL23886300 0.77 CHRM3 (0.37) CA2KCNN4ACHE
Hydrochloric Acid SCHEMBL29168009 0.77 HTR2C (0.37) CA2KCNN4ACHE
SCHEMBL7762883 0.76 KCNN4 (0.44) KCNN4
SCHEMBL1198277 0.76 TAS2R14 (0.41) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0701554-B1 NOVEL COMPOUNDS HAVING A BENZISOSELEN-AZOLINE AND -AZINE STRUCTURE, METHOD FOR PREPARING SAME AND THERAPEUTIC USES THEREOF OXIS ISLE OF MAN LTD (GB) 2001-06-27 EP disclosed
US-6093532-A USING ADAPTED STORAGE MEDIUM WHICH SUPPLIES SELENIUM FOR GLUTATHIONE PEROXIDASE, A CRYOPROTECTIVE AND ANTIOXIDANT ENZYME OXIS ISLE OF MAN, LIMITED (US) 2000-07-25 US disclosed
US-5968920-A INCREASE GLUTATHIONE PEROXIDASE ACTIVITY FOR REDUCING LEVELS OF PEROXIDES IN CELLS OR TISSUES OXIS ISLE OF MAN, LIMITED (US) 1999-10-19 US disclosed