Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7763851 | 0.89 | CA1 (0.47) | KMT2ASMN1; SMN2MEN1RAB9ANPC1 | |
| SCHEMBL7771479 | 0.85 | MAPT (0.57) | KMT2ASMN1; SMN2MEN1RAB9ANPC1 | |
| SCHEMBL7763850 | 0.84 | MAPT (0.50) | KMT2ASMN1; SMN2MEN1RAB9ANPC1 | |
| SCHEMBL7767116 | 0.81 | MAPT (0.53) | KMT2ASMN1; SMN2MEN1RAB9ANPC1 | |
| SCHEMBL7771429 | 0.81 | MAPT (0.53) | KMT2ASMN1; SMN2MEN1RAB9ANPC1 | |
| SCHEMBL7763838 | 0.81 | DRD2 (0.43) | SMN1; SMN2RAB9ANPC1MAPTMAOB | |
| SCHEMBL978502 | 0.80 | RAB9A (0.71) | KMT2ASMN1; SMN2MEN1RAB9ANPC1 | |
| SCHEMBL7771500 | 0.79 | MAPT (0.47) | KMT2ASMN1; SMN2MEN1RAB9ANPC1 | |
| SCHEMBL7771472 | 0.78 | SMPD1 (0.44) | KMT2ASMN1; SMN2MEN1RAB9ANPC1 | |
| SCHEMBL10760418 | 0.77 | ALOX5 (0.42) | SMN1; SMN2RAB9ANPC1MAOBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741128-B1 | Sulphuric acid esters of sugar alcohols for the inhibition of the migration and proliferation of smooth muscle cells of the vascular walls | HOFFMANN LA ROCHE (CH) | 2001-06-20 | — | — | EP | disclosed |
| US-5830920-A | PREVENTION GROWTH OF SMOOTH MUSCLE CELLS | HOFFMANN-LA ROCHE INC. (US) | 1998-11-03 | — | — | US | disclosed |
| CN-1150589-A | New sulfuric acid esters of sugar alcohols | HOFFMANN LA ROCHE (CH) | 1997-05-28 | — | — | CN | disclosed |
| EP-0741128-A2 | Sulphuric acid esters of sugar alcohols for the inhibition of the migration and proliferation of smooth muscle cells of the vascular walls | F. HOFFMANN-LA ROCHE AG (CH) | 1996-11-06 | — | — | EP | disclosed |