Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Formic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SNCA | P37840 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL28324384 | 0.94 | ALDH1A1 (0.47) | GAATLR9ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL9517473 | 0.91 | GAA (0.52) | GAATLR9ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5068661 | 0.91 | GAA (0.62) | GAATLR9ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL31313 | 0.91 | GAA (0.62) | GAATLR9ALDH1A1SMN1; SMN2LMNA | |
| P-Xylene SCHEMBL8660591 | 0.91 | GAA (0.62) | GAATLR9ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL29991938 | 0.91 | GAA (0.62) | GAATLR9ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11432043 | 0.91 | GAA (0.62) | GAATLR9ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1705904 | 0.91 | GAA (0.62) | GAATLR9ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL34 | 0.91 | GAA (0.62) | GAATLR9ALDH1A1SMN1; SMN2LMNA | |
| Phosphine SCHEMBL3185895 | 0.88 | GAA (0.59) | GAATLR9ALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160115601-A1 | ELECTROCHEMICAL PROCESS FOR PRODUCTION OF GRAPHENE | UNIV MANCHESTER (GB) | 2016-04-28 | — | — | US | claimed |
| EP-3004423-A1 | ELECTROCHEMICAL PROCESS FOR PRODUCTION OF GRAPHENE | The University Of Manchester (GB) | 2016-04-13 | — | — | EP | claimed |
| WO-2014191765-A1 | ELECTROCHEMICAL PROCESS FOR PRODUCTION OF GRAPHENE | THE UNIVERSITY OF MANCHESTER (GB) | 2014-12-04 | — | — | WO | claimed |
| EP-3030693-B1 | PRODUCTION OF GRAPHENE AND GRAPHANE | UNIV MANCHESTER (GB) | 2020-05-13 | — | — | EP | disclosed |
| CN-110382485-A | Heterocycle ene derivative as pest control agent | 拜耳公司 | 2019-10-25 | — | — | CN | disclosed |
| CN-110312718-A | HETEROCYCLENE DERIVATIVES AS PEST CONTROL AGENTS | 拜耳公司 | 2019-10-08 | — | — | CN | disclosed |
| CN-106414441-B9 | 2- (hetero) aryl-substituted fused bicyclic heterocyclic derivatives as pest control agents | 拜耳作物科学股份公司 | 2019-09-20 | — | — | CN | disclosed |
| CN-110248941-A | The imidazopyridine derivatives that aryl or heteroaryl replace and its purposes as pesticide | 拜耳公司 | 2019-09-17 | — | — | CN | disclosed |
| US-10415143-B2 | Production of graphene and graphane | THE UNIVERSITY OF MANCHESTER (GB) | 2019-09-17 | — | — | US | disclosed |
| CN-106414441-B | 2- (hetero) aryl-substituted fused bicyclic heterocyclic derivatives as pest control agents | 拜耳作物科学股份公司 | 2019-08-13 | — | — | CN | disclosed |
| CN-110062756-A | 2- (hetero) aryl-substituted fused bicyclic heterocyclic derivatives as pest control agents | 拜耳作物科学股份公司 | 2019-07-26 | — | — | CN | disclosed |
| EP-3004423-A1 | ELECTROCHEMICAL PROCESS FOR PRODUCTION OF GRAPHENE | The University Of Manchester (GB) | 2016-04-13 | — | — | EP | disclosed |
| WO-2015019093-A1 | PRODUCTION OF GRAPHENE AND GRAPHANE | THE UNIVERSITY OF MANCHESTER (GB) | 2015-02-12 | — | — | WO | disclosed |
| WO-2014191765-A1 | ELECTROCHEMICAL PROCESS FOR PRODUCTION OF GRAPHENE | THE UNIVERSITY OF MANCHESTER (GB) | 2014-12-04 | — | — | WO | disclosed |
| EP-1112303-A2 | CURING OF RESINS | Chemcolloids Limited (GB) | 2001-07-04 | — | — | EP | disclosed |
| CN-1287117-A | Cyclobutene derivatives, preparation method and therapeutic use thereof | SANKYO CO (JP) | 2001-03-14 | — | — | CN | disclosed |
| WO-2000015694-A2 | CURING OF RESINS | CHEMCOLLOIDS LIMITED (GB) | 2000-03-23 | — | — | WO | disclosed |
| WO-1998006723-A1 | AMINE SALTS | BIOCHEMIE GESELLSCHAFT MBH (AT) | 1998-02-19 | — | — | WO | disclosed |
| EP-0009548-A2 | Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-04-16 | — | — | EP | disclosed |
| US-4104280-A | Dibenzo [b.f]thiepin and dibenzo[b.f]oxepin derivatives | SYNTEX (U.S.A.) INC. (US) | 1978-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10415143-B2 | Production of graphene and graphane | GRN, GYPA, GJA1 | GAA 3249/4885TLR9 2117/4885ALDH1A1 2880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.