Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7847009 | 0.88 | CA12 (0.39) | HTTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL6792314 | 0.85 | CA12 (0.43) | HTTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7770465 | 0.85 | LMNA (0.35) | HTTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7844950 | 0.84 | KDM4E (0.36) | HTTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL7764703 | 0.84 | TP53 (0.37) | HTTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7764765 | 0.84 | TP53 (0.37) | HTTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8117763 | 0.81 | GRK6 (0.32) | ALDH1A1MEN1KMT2ALMNAHPGD | |
| SCHEMBL7836776 | 0.81 | SMN1; SMN2 (0.32) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL9114805 | 0.80 | KDM4E (0.40) | ALDH1A1MEN1KMT2ALMNAHPGD | |
| SCHEMBL6793677 | 0.79 | KIF11 (0.37) | HTTKMT2ALMNARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112264-A1 | POLYALKOXYLATED NAPHTHOPYRANS | TRANSITIONS OPTICAL, INC. (US) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000015630-A1 | POLYALKOXYLATED NAPHTHOPYRANS | PPG INDUSTRIES OHIO, INC. (US) | 2000-03-23 | — | — | WO | disclosed |