Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9111945 | 0.90 | NCEH1 (0.34) | KDM4EHSD17B10KMT2AMEN1ALDH1A1 | |
| SCHEMBL7839463 | 0.88 | L3MBTL1 (0.38) | KDM4EHSD17B10KMT2AL3MBTL1CA12 | |
| SCHEMBL7456709 | 0.87 | KMT2A (0.42) | KDM4EKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL7770465 | 0.86 | LMNA (0.35) | KDM4EKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL6792314 | 0.86 | CA12 (0.43) | KDM4EHSD17B10KMT2AMEN1ALDH1A1 | |
| SCHEMBL7768682 | 0.84 | HTT (0.40) | KDM4EHSD17B10KMT2AMEN1ALDH1A1 | |
| SCHEMBL9114805 | 0.83 | KDM4E (0.40) | KDM4EHSD17B10KMT2AMEN1ALDH1A1 | |
| SCHEMBL8117763 | 0.82 | GRK6 (0.32) | KDM4EKMT2AMEN1ALDH1A1CA12 | |
| SCHEMBL7847009 | 0.82 | CA12 (0.39) | KDM4EHSD17B10KMT2AMEN1ALDH1A1 | |
| SCHEMBL7452626 | 0.82 | NCEH1 (0.34) | KDM4EKMT2AMEN1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097155-A2 | PHOTOCHROMIC SIX-MEMBERED HETEROCYCLIC-FUSED NAPHTHOPYRANS | TRANSITIONS OPTICAL, INC. (US) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000002883-A2 | PHOTOCHROMIC SIX-MEMBERED HETEROCYCLIC-FUSED NAPHTHOPYRANS | TRANSITIONS OPTICAL, INC. (US) | 2000-01-20 | — | — | WO | disclosed |