Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | PRCP | P42785 | 1/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7764703 | 1.00 | TP53 (0.37) | TP53TSHRCAPN1SMN1; SMN2MEN1 | |
| SCHEMBL7764719 | 0.88 | TSHR (0.38) | TP53TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7817869 | 0.88 | MGLL (0.34) | — | |
| SCHEMBL7768682 | 0.84 | HTT (0.40) | TSHRSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL6792314 | 0.71 | CA12 (0.43) | TP53TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7770465 | 0.71 | LMNA (0.35) | TP53TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7844950 | 0.70 | KDM4E (0.36) | TSHRMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7596981 | 0.69 | TP53 (0.41) | TP53TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7597572 | 0.69 | TP53 (0.41) | TP53TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8117763 | 0.68 | GRK6 (0.32) | TSHRSMN1; SMN2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112264-A1 | POLYALKOXYLATED NAPHTHOPYRANS | TRANSITIONS OPTICAL, INC. (US) | 2001-07-04 | — | — | EP | claimed |
| WO-2000015630-A1 | POLYALKOXYLATED NAPHTHOPYRANS | PPG INDUSTRIES OHIO, INC. (US) | 2000-03-23 | — | — | WO | claimed |
| EP-1112264-A1 | POLYALKOXYLATED NAPHTHOPYRANS | TRANSITIONS OPTICAL, INC. (US) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000015630-A1 | POLYALKOXYLATED NAPHTHOPYRANS | PPG INDUSTRIES OHIO, INC. (US) | 2000-03-23 | — | — | WO | disclosed |