Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8750297 | 0.84 | BRD4 (0.33) | HSD17B10MEN1USP2TSHRKMT2A | |
| SCHEMBL8750285 | 0.82 | KCNA3 (0.32) | HSD17B10MEN1USP2TSHRKMT2A | |
| SCHEMBL11522239 | 0.82 | MEN1 (0.43) | HSD17B10MEN1USP2TSHRKMT2A | |
| SCHEMBL7768685 | 0.82 | SMN1; SMN2 (0.37) | POLBAPEX1BLMALDH1A1 | |
| SCHEMBL692641 | 0.76 | POLB (0.57) | HSD17B10MAPTMAPK1POLBALDH1A1 | |
| SCHEMBL8271284 | 0.76 | POLB (0.57) | HSD17B10MAPTMAPK1POLBALDH1A1 | |
| SCHEMBL688493 | 0.75 | POLB (0.60) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL13280491 | 0.74 | POLB (0.55) | HSD17B10MAPTMAPK1POLBALDH1A1 | |
| SCHEMBL3700318 | 0.74 | L3MBTL1 (0.47) | MEN1KMT2AMAPK1POLBALDH1A1 | |
| SCHEMBL10628769 | 0.73 | APEX1 (0.53) | HSD17B10MEN1USP2TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2028247-A1 | Use of 1-alkyl-5-oxo-pyrrolidine-3-carbolic acid esters as gas hydrate inhibitors with improved biological degradability | CLARIANT INTERNATIONAL LTD. (CH) | 2009-02-25 | — | — | EP | claimed |
| EP-2615911-A1 | PESTICIDE PREPARATIONS CONTAINING N-SUBSTITUTED 2-PYRROLIDONE-4-CARBONIC ACID ESTERS | Clariant Finance (BVI) Limited (VG) | 2013-07-24 | — | — | EP | disclosed |
| EP-2616438-A1 | USE OF N-SUBSTITUTED 2-PYRROLIDONE-4-CARBONIC ACID ESTERS AS SOLVENTS | Clariant Finance (BV) Limited (VG) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012034689-A1 | PESTICIDE PREPARATIONS CONTAINING N-SUBSTITUTED 2-PYRROLIDONE-4-CARBONIC ACID ESTERS | CLARIANT INTERNATIONAL LTD (CH) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012034688-A1 | USE OF N-SUBSTITUTED 2-PYRROLIDONE-4-CARBONIC ACID ESTERS AS SOLVENTS | CLARIANT INTERNATIONAL LTD (CH) | 2012-03-22 | — | — | WO | disclosed |
| EP-2022781-B1 | 1-Alkyl-5-oxo-pyrrolidine-3-carboxylic acid esters with improved biodegradability | CLARIANT FINANCE BVI LTD (VG) | 2012-02-29 | — | — | EP | disclosed |
| EP-2022781-B1 | 1-Alkyl-5-oxo-pyrrolidine-3-carboxylic acid esters with improved biodegradability | CLARIANT FINANCE BVI LTD (VG) | 2012-02-29 | — | — | EP | disclosed |
| EP-2031035-A1 | Use of substituted polyethyl enemines as gas hydrate inhibitors with improved biological degradability | CLARIANT INTERNATIONAL LTD. (CH) | 2009-03-04 | — | — | EP | disclosed |
| EP-2028247-A1 | Use of 1-alkyl-5-oxo-pyrrolidine-3-carbolic acid esters as gas hydrate inhibitors with improved biological degradability | CLARIANT INTERNATIONAL LTD. (CH) | 2009-02-25 | — | — | EP | disclosed |
| EP-2028247-A1 | Use of 1-alkyl-5-oxo-pyrrolidine-3-carbolic acid esters as gas hydrate inhibitors with improved biological degradability | CLARIANT INTERNATIONAL LTD. (CH) | 2009-02-25 | — | — | EP | disclosed |
| EP-2022781-A1 | 1-Alkyl-5-oxo-pyrrolidine-3-carboxylic acid esters with improved biodegradability | CLARIANT INTERNATIONAL LTD. (CH) | 2009-02-11 | — | — | EP | disclosed |
| EP-2022781-A1 | 1-Alkyl-5-oxo-pyrrolidine-3-carboxylic acid esters with improved biodegradability | CLARIANT INTERNATIONAL LTD. (CH) | 2009-02-11 | — | — | EP | disclosed |