Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7110470 | 0.86 | MEN1 (0.43) | MEN1KMT2ACACNA1BALDH1A1LMNA | |
| SCHEMBL7105591 | 0.86 | MEN1 (0.43) | MEN1KMT2ACACNA1BALDH1A1LMNA | |
| SCHEMBL7110901 | 0.86 | MEN1 (0.43) | MEN1KMT2ACACNA1BALDH1A1LMNA | |
| SCHEMBL7768824 | 0.85 | KMT2A (0.42) | MEN1KMT2ACACNA1BALDH1A1LMNA | |
| SCHEMBL7105628 | 0.84 | MEN1 (0.45) | MEN1KMT2ACACNA1BALDH1A1LMNA | |
| SCHEMBL7112266 | 0.78 | MEN1 (0.40) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL7110494 | 0.78 | CACNA1B (0.50) | MEN1KMT2ACACNA1BMCL1 | |
| SCHEMBL7768814 | 0.78 | CACNA1B (0.39) | MEN1KMT2ACACNA1BALDH1A1POLB | |
| SCHEMBL7109484 | 0.77 | USP21 (0.40) | MEN1KMT2ACACNA1BMCL1 | |
| SCHEMBL7111673 | 0.77 | YAP1 (0.46) | CACNA1BMCL1PSMB8PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097929-A1 | AMINO ACID DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-05-09 | — | — | EP | disclosed |