SCHEMBL7768911

SCHEMBL7768911

Ic1ccccc1-c1nnn[nH]1

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 1/20 0.35
F2 P00734 1/20 0.33
C1R P00736 1/20 0.33
PLG P00747 1/20 0.33
KLK1 P06870 1/20 0.33
PRSS1 P07477 1/20 0.33
C1S P09871 1/20 0.33
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
KMT2A Q03164 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12615990 0.85 ALDH1A1 (0.38) MEN1ALDH1A1KMT2AL3MBTL1
SCHEMBL1773419 0.76 IDO1 (0.52) MEN1ALDH1A1KMT2A
SCHEMBL3397570 0.76 DCUN1D1 (0.47) ALDH1A1
SCHEMBL2644624 0.76 MEN1 (0.32) MEN1ALDH1A1KMT2AL3MBTL1
SCHEMBL918324 0.76 DCUN1D1 (0.47) MEN1ALDH1A1KMT2A
SCHEMBL23161505 0.76 MEN1 (0.36) MEN1ALDH1A1KMT2AL3MBTL1
SCHEMBL704887 0.76 DCUN1D1 (0.47) KCNN4MEN1ALDH1A1KMT2A
SCHEMBL1774388 0.76 DCUN1D1 (0.47) ALDH1A1KMT2A
SCHEMBL8326262 0.76 IDO1 (0.39) MEN1ALDH1A1KMT2AL3MBTL1
SCHEMBL9389043 0.76 MEN1 (0.32) MEN1ALDH1A1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0788487-B1 PROCESS FOR THE PREPARATION OF TETRAZOLES NOVARTIS AG (CH) 2001-07-25 EP disclosed
EP-0788487-A1 PROCESS FOR THE PREPARATION OF TETRAZOLES Novartis AG (CH) 1997-08-13 EP disclosed
WO-1996013489-A1 PROCESS FOR THE PREPARATION OF TETRAZOLES NOVARTIS AG (CH) 1996-05-09 WO disclosed