Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.47 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MPI | P34949 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30915513 | 1.00 | DCUN1D1 (0.47) | DCUN1D1PBRM1NR1H2NR1H3ALDH1A1 | |
| SCHEMBL12615990 | 0.85 | ALDH1A1 (0.38) | DCUN1D1PBRM1ALDH1A1GAAIDO1 | |
| SCHEMBL5096254 | 0.81 | ALDH1A1 (0.44) | DCUN1D1PBRM1NR1H2NR1H3ALDH1A1 | |
| SCHEMBL1774388 | 0.76 | DCUN1D1 (0.47) | DCUN1D1NR1H2NR1H3ALDH1A1HPGD | |
| SCHEMBL3397570 | 0.76 | DCUN1D1 (0.47) | DCUN1D1NR1H2NR1H3ALDH1A1MAPK1 | |
| SCHEMBL23161505 | 0.76 | MEN1 (0.36) | PBRM1ALDH1A1GAAIDO1MEN1 | |
| SCHEMBL8326262 | 0.76 | IDO1 (0.39) | ALDH1A1IDO1MEN1KMT2A | |
| SCHEMBL918324 | 0.76 | DCUN1D1 (0.47) | DCUN1D1ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL1773419 | 0.76 | IDO1 (0.52) | DCUN1D1ALDH1A1MAPK1MAPTHPGD | |
| SCHEMBL7768911 | 0.76 | KCNN4 (0.35) | ALDH1A1MEN1KMT2AKCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 193 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9724673-B2 | Supported alkoxylated organotin reactant, preparation and use for heterogeneous-phase synthesis of tetrazoles | UNIVERSITE DE NANTES (FR) | 2017-08-08 | — | — | US | claimed |
| CN-104447599-B | A kind of tetrazole heterogeneous ring compound and preparation method thereof | ANHUI NORMAL UNIVERSITY (CN) | 2016-04-27 | — | — | CN | claimed |
| EP-2726515-B1 | SUPPORTED ALKOXYLATED ORGANOTIN REACTANT, PREPARATION AND USE FOR HETEROGENEOUS-PHASE SYNTHESIS OF TETRAZOLES | CENTRE NAT RECH SCIENT (FR) | 2015-04-01 | — | — | EP | claimed |
| CN-104447599-A | Tetrazole heterocyclic compound and preparation method thereof | UNIV ANHUI NORMAL | 2015-03-25 | — | — | CN | claimed |
| US-20140206825-A1 | SUPPORTED ALKOXYLATED ORGANOTIN REACTANT, PREPARATION AND USE FOR HETEROGENEOUS-PHASE SYNTHESIS OF TETRAZOLES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-07-24 | — | — | US | claimed |
| EP-2726515-A1 | SUPPORTED ALKOXYLATED ORGANOTIN REACTANT, PREPARATION AND USE FOR HETEROGENEOUS-PHASE SYNTHESIS OF TETRAZOLES | Centre National De La Recherche Scientifique (FR) | 2014-05-07 | — | — | EP | claimed |
| WO-2013001235-A1 | SUPPORTED ALKOXYLATED ORGANOTIN REACTANT, PREPARATION AND USE FOR HETEROGENEOUS-PHASE SYNTHESIS OF TETRAZOLES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-01-03 | — | — | WO | claimed |
| US-20240308988-A1 | Method For Controlling Diamide Resistant Pests and Compounds Therefor | SYNGENTA CROP PROTECTION AG (CH) | 2024-09-19 | — | — | US | disclosed |
| CN-118359555-A | Preparation method of valsartan intermediate | 南京一心和医药科技有限公司 | 2024-07-19 | — | — | CN | disclosed |
| EP-4380363-A1 | METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR | Syngenta Crop Protection AG (CH) | 2024-06-12 | — | — | EP | disclosed |
| CN-118076228-A | Methods for controlling diamide-resistant pests and compounds thereof | 先正达农作物保护股份公司 | 2024-05-24 | — | — | CN | disclosed |
| WO-2023012081-A1 | METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR | SYNGENTA CROP PROTECTION AG (CH) | 2023-02-09 | — | — | WO | disclosed |
| US-10364256-B2 | Biaryl pyrazoles as NRF2 regulators | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-07-30 | — | — | US | disclosed |
| US-5155117-A | Hypotensive agents | G. D. SEARLE & CO. (US) | 1992-10-13 | — | — | US | disclosed |
| WO-1992016523-A1 | 5-ARYLHETEROARYLALKYL-1,3,5-TRISUBSTITUTED-1,2,4-TRIAZOLE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1992-10-01 | — | — | WO | disclosed |
| EP-0504888-A1 | 5-Arylheteroarylalkyl-1,3,5-trisubstituted-1,2,4-triazole compounds for treatment of circulatory disorders | G.D. Searle & Co. (US) | 1992-09-23 | — | — | EP | disclosed |
| US-5149699-A | Substituted pyridopyrimidines useful as antgiotensin II antagonists | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-09-22 | — | — | US | disclosed |
| EP-0497150-A1 | Angiotensin II receptor blocking 2,3,6-substituted quinazolones | AMERICAN CYANAMID COMPANY (US) | 1992-08-05 | — | — | EP | disclosed |
| EP-0455423-A2 | Ortho-lithiation process for the synthesis of 2-substituted 1-(tetrazol-5-yl) benzenes | MERCK & CO. INC. (US) | 1991-11-06 | — | — | EP | disclosed |
| US-5039814-A | Chemical intermediates for angiotensin antagonist | MERCK & CO., INC. (US) | 1991-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240308988-A1 | Method For Controlling Diamide Resistant Pests and Compounds Therefor | DDT, NOS1, SLC11A2 | DCUN1D1 58/4885PBRM1 1907/4885NR1H2 2748/4885 |
| US-10364256-B2 | Biaryl pyrazoles as NRF2 regulators | NFE2L2, KEAP1, NQO1 | DCUN1D1 3396/4885PBRM1 2346/4885NR1H2 33/4885 |
| US-20140206825-A1 | SUPPORTED ALKOXYLATED ORGANOTIN REACTANT, PREPARATION AND USE FOR HETEROGENEOUS-PHASE SYNTHESIS OF TETRAZOLES | ALK, TST, TEKT1 | DCUN1D1 991/4885PBRM1 794/4885NR1H2 3954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.