Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.41 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.41 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 9/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1938624 | 0.84 | VCAM1 (0.42) | TSHRALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL4859459 | 0.82 | GPR35 (0.42) | TSHRALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL1185703 | 0.82 | VCAM1 (0.49) | TSHRALDH1A1CYP3A4HPGDALOX15 | |
| Silver SCHEMBL2515251 | 0.82 | GPR35 (0.38) | TSHRALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL2515254 | 0.81 | GPR35 (0.41) | TSHRALDH1A1CYP3A4HPGDALOX15 | |
| Hydrochloric Acid SCHEMBL27566213 | 0.81 | GPR35 (0.41) | TSHRALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL7764312 | 0.79 | ALDH1A1 (0.37) | TSHRALDH1A1CYP3A4ALOX15TDP1 | |
| SCHEMBL15880676 | 0.78 | CA1 (0.53) | TSHRALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL5233687 | 0.78 | VCAM1 (0.36) | TSHRALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL5232126 | 0.75 | EPAS1 (0.40) | ALDH1A1TDP1VCAM1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0740690-B1 | MONOAZO DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF | SYNGENTA LTD (GB) | 2001-06-20 | — | — | EP | disclosed |
| US-5739299-A | GOOD WET FASTNESS AND LIGHT FASTNESS PROPERTIES | ZENECA LIMITED (GB) | 1998-04-14 | — | — | US | disclosed |
| EP-0740690-A1 | MONOAZO DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF | ZENECA LIMITED (GB) | 1996-11-06 | — | — | EP | disclosed |
| WO-1995020014-A1 | MONOAZO DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF | ZENECA LIMITED (GB) | 1995-07-27 | — | — | WO | disclosed |