Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2598199 | 0.79 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2MAPTMAPK1SLC6A3 | |
| SCHEMBL4939408 | 0.77 | LTB4R2 (0.41) | GPR119ALDH1A1SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL15539307 | 0.72 | PTPN1 (0.37) | GPR119ALDH1A1SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL31722799 | 0.71 | BDKRB1 (0.47) | ALDH1A1SMN1; SMN2MAPTMAPK1CRHBP | |
| SCHEMBL2598198 | 0.71 | BDKRB1 (0.47) | ALDH1A1SMN1; SMN2MAPTMAPK1CRHBP | |
| SCHEMBL8417432 | 0.70 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2MAPTLMNATDP1 | |
| SCHEMBL27488491 | 0.69 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2MAPTMAPK1LMNA | |
| SCHEMBL7771116 | 0.68 | LTB4R2 (0.42) | GPR119ALDH1A1LMNAPTPN1 | |
| SCHEMBL6165708 | 0.68 | ESR2 (0.56) | GPR119ALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL3974369 | 0.68 | SLC6A3 (0.49) | ALDH1A1SMN1; SMN2MAPTMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0881212-B1 | Production method of aminobenzene compound | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-10-31 | — | — | EP | disclosed |
| US-6177587-B1 | INTERMEDIATES FOR THE PRODUCTION OF MEDICINES; REACTING A MIXTURE CONTAINING A MONO-HALOGENO COMPOUND OR A DI-HALOGENO COMPOUND WITH AN AMIDO NITROBENZENE DERIVATIVE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-23 | — | — | US | disclosed |
| EP-0881212-A1 | Production method of aminobenzene compound | Takeda Chemical Industries, Ltd. (JP) | 1998-12-02 | — | — | EP | disclosed |