Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7769535 | 0.87 | LMNA (0.33) | DRD2DRD4GPR84LMNA | |
| SCHEMBL7769523 | 0.80 | DRD2 (0.44) | DRD2DRD4GPR84LMNA | |
| SCHEMBL7769084 | 0.75 | LMNA (0.53) | DRD2DRD4GPR84LMNA | |
| SCHEMBL18516202 | 0.71 | MAPK1 (0.44) | — | |
| SCHEMBL21764489 | 0.71 | MAPK1 (0.44) | — | |
| SCHEMBL7769086 | 0.71 | GPR84 (0.39) | GPR84LMNA | |
| SCHEMBL7769544 | 0.69 | TRPA1 (0.41) | DRD2DRD4GPR84LMNA | |
| SCHEMBL7770728 | 0.69 | DRD2 (0.43) | DRD2DRD4GPR84LMNA | |
| SCHEMBL380544 | 0.66 | — | — | |
| SCHEMBL18489010 | 0.66 | AHR (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726265-B1 | 10-Aminoaliphatyl-dibenz(b,f)oxepins with antineurodegenarative activity | NOVARTIS AG (CH) | 2001-07-25 | — | — | EP | disclosed |
| EP-0726265-A1 | 10-Aminoaliphatyl-dibenz(b,f)oxepins with antineurodegenarative activity | CIBA-GEIGY AG (CH) | 1996-08-14 | — | — | EP | disclosed |