Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | CTSC | P53634 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7769750 | 1.00 | TDP1 (0.52) | TDP1MAOAMAOBCARM1PRMT6 | |
| SCHEMBL1609623 | 0.89 | MAOA (0.58) | MAOAMAOBCARM1PRMT6CTSL | |
| SCHEMBL705394 | 0.81 | CTSS (0.56) | MAOAMAOBCTSSCTSKOPRM1 | |
| SCHEMBL7756938 | 0.81 | OPRM1 (0.58) | MAOAMAOBCTSSCTSKOPRM1 | |
| SCHEMBL240002 | 0.80 | MAOA (0.50) | MAOAMAOBCARM1PRMT6CTSL | |
| SCHEMBL19188155 | 0.80 | MAOA (0.50) | MAOAMAOBCARM1PRMT6CTSL | |
| SCHEMBL10455153 | 0.80 | MAOA (0.50) | MAOAMAOBCARM1PRMT6CTSL | |
| SCHEMBL16499615 | 0.80 | MAOA (0.50) | TDP1MAOAMAOBCARM1PRMT6 | |
| SCHEMBL9163690 | 0.80 | CARM1 (0.51) | MAOAMAOBCARM1PRMT6 | |
| SCHEMBL16499700 | 0.80 | MAOA (0.50) | TDP1MAOAMAOBCARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727428-B1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHINETSU CHEMICAL CO (JP) | 2001-06-06 | — | — | EP | disclosed |
| US-5665271-A | Silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-09-09 | — | — | US | disclosed |
| EP-0727428-A1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-08-21 | — | — | EP | disclosed |