Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.31 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.31 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.31 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25208944 | 0.79 | EGLN1 (0.42) | — | |
| SCHEMBL7769360 | 0.78 | ACHE (0.35) | MAOAMAOBPRSS1TPSAB1 | |
| SCHEMBL7773720 | 0.78 | ACHE (0.42) | — | |
| SCHEMBL7769849 | 0.77 | — | — | |
| SCHEMBL7769472 | 0.77 | ALOX15 (0.48) | — | |
| SCHEMBL7771590 | 0.77 | ACHE (0.42) | MAOAMAOB | |
| SCHEMBL7769455 | 0.75 | ACHE (0.41) | MAOAMAOB | |
| SCHEMBL7773559 | 0.74 | ACHE (0.48) | — | |
| SCHEMBL7770971 | 0.74 | ALDH1A1 (0.42) | MAOAMAOB | |
| SCHEMBL7770881 | 0.74 | ALDH1A1 (0.42) | MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |