Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ECE1 | P42892 | 1/20 | 0.31 |
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | PGK2 | P07205 | 1/20 | 0.31 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9749703 | 0.79 | ECE1 (0.45) | LMNAALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL5544335 | 0.77 | POLB (0.42) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7771469 | 0.77 | ALDH1A1 (0.60) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7769403 | 0.76 | LMNA (0.34) | LMNAALDH1A1 | |
| SCHEMBL2746099 | 0.76 | ECE1 (0.33) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL10438919 | 0.74 | LMNA (0.38) | LMNAALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL13660344 | 0.73 | MEN1 (0.58) | LMNAALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL13660337 | 0.73 | MEN1 (0.58) | LMNAALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL13660345 | 0.73 | MEN1 (0.58) | LMNAALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL4280908 | 0.73 | LMNA (0.43) | LMNAALDH1A1POLBSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |