Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11685139 | 0.77 | EGLN1 (0.39) | LMNAL3MBTL1ALDH1A1TP53TSHR | |
| SCHEMBL7770037 | 0.76 | LMNA (0.40) | LMNAALDH1A1 | |
| SCHEMBL4948924 | 0.76 | — | — | |
| SCHEMBL7769400 | 0.75 | LMNA (0.34) | LMNAL3MBTL1ALDH1A1TP53TSHR | |
| SCHEMBL28639418 | 0.75 | L3MBTL1 (0.40) | LMNAL3MBTL1ALDH1A1TP53TSHR | |
| SCHEMBL5544499 | 0.75 | MAOA (0.38) | MAOAMAOBL3MBTL1 | |
| SCHEMBL130951 | 0.75 | ALDH1A1 (0.52) | MAOAMAOBALDH1A1 | |
| SCHEMBL2745500 | 0.73 | MAOA (0.37) | MAOAMAOB | |
| SCHEMBL11518432 | 0.70 | — | — | |
| SCHEMBL12575372 | 0.70 | RIPK1 (0.46) | LMNAMAOAMAOBALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3010889-A1 | ARYL SULFIDE DERIVATIVES AND ARYL SULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2016-04-27 | — | — | EP | disclosed |
| WO-2014202505-A1 | ARYL SULFIDE DERIVATIVES AND ARYL SULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2014-12-24 | — | — | WO | disclosed |
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |