SCHEMBL7770072

SCHEMBL7770072

O=C(Nc1ccccc1)Nc1ccc(S(=O)(=O)NC(=O)c2ccc(O)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.61
MAOB P27338 1/20 0.61
LMNA P02545 2/20 0.56
KMT2A Q03164 4/20 0.55
MEN1 O00255 3/20 0.55
FLT1 P17948 2/20 0.55
FLT4 P35916 2/20 0.55
KDR P35968 2/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
SIRT1 Q96EB6 1/20 0.54
CA1 P00915 3/20 0.54
CA2 P00918 3/20 0.54
CA9 Q16790 3/20 0.54
CA12 O43570 1/20 0.54
DEGS1 O15121 1/20 0.52
CYP2C9 P11712 1/20 0.52
ALDH1A1 P00352 1/20 0.52
KDM4E B2RXH2 1/20 0.51
POLB P06746 1/20 0.51
CTDSP1 Q9GZU7 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7776312 1.00 MAOA (0.61) MAOAMAOBLMNAKMT2AMEN1
SCHEMBL6295675 0.91 SIRT1 (0.60) LMNAKMT2AMEN1FLT1FLT4
SCHEMBL6295620 0.91 MEN1 (0.65) LMNAKMT2AMEN1FLT1FLT4
SCHEMBL7774811 0.89 GAA (0.62) MAOAMAOBLMNAKMT2AMEN1
SCHEMBL7774521 0.88 LMNA (0.74) LMNAKMT2AMEN1CA1CA2
SCHEMBL7647250 0.88 LMNA (0.74) LMNAKMT2AMEN1CA1CA2
SCHEMBL7776317 0.88 MEN1 (0.60) LMNAKMT2AMEN1CA1CA2
SCHEMBL8767401 0.87 KAT6A (0.60) LMNAKMT2AMEN1CA1CA2
SCHEMBL7774533 0.86 L3MBTL1 (0.47) MAOAMAOBLMNAKMT2AMEN1
SCHEMBL8659346 0.84 HSD17B10 (0.67) LMNAKMT2AMEN1KDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0788889-B1 A thermal sensitive recording sheet JUJO PAPER CO LTD (JP) 2001-08-08 EP disclosed
EP-0699662-B1 Novel urea (thiourea) derivative and thermal recording sheet using same JUJO PAPER CO LTD (JP) 1998-10-21 EP disclosed
US-5661100-A HAVING HIGH SENSITIVITY, SUPERIOR THERMAL RESISTANCE, WATER RESISTANCE, OIL RESISTANCE NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1997-08-26 US disclosed
EP-0788889-A2 A thermal sensitive recording sheet NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1997-08-13 EP disclosed
EP-0699662-A1 Novel urea (thiourea) derivative and thermal recording sheet using same NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1996-03-06 EP disclosed