Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 10/20 | 0.68 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CCR9 | P51686 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mipitroban SCHEMBL1229504 | 0.81 | TBXA2R (1.00) | TBXA2R | |
| SCHEMBL2223565 | 0.70 | PPARA (0.49) | MAPTMEN1KMT2AGAAPTGES2 | |
| SCHEMBL9581586 | 0.67 | TBXA2R (0.67) | TBXA2R | |
| SCHEMBL23630652 | 0.67 | ALOX5AP (0.49) | TBXA2RMAPTALOX5APPTGES2KDM4E | |
| SCHEMBL20508674 | 0.67 | BRD4 (0.60) | TBXA2RLMNAKMT2ARAB9ABRD4 | |
| SCHEMBL9701529 | 0.66 | TBXA2R (1.00) | TBXA2RENPP2MAPTMEN1LMNA | |
| SCHEMBL9737953 | 0.65 | PTGES2 (0.82) | TBXA2RMAPTPTGES2KDM4ECYP1A2 | |
| SCHEMBL22728703 | 0.65 | PPARA (0.54) | MAPTMEN1KMT2APTGES2CYP1A2 | |
| SCHEMBL21533486 | 0.65 | APEX1 (0.47) | TBXA2RMAPTMEN1LMNAKMT2A | |
| SCHEMBL27925889 | 0.65 | ALDH1A1 (0.53) | MAPTMEN1LMNAKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001089519-A1 | THROMBOXANE INHIBITORS, COMPOSITIONS AND METHODS OF USE RELATED APPLICATIONS | NITROMED, INC. (US) | 2001-11-29 | — | — | WO | claimed |