Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7770327 | 1.00 | MAPT (0.54) | MAPTMEN1KMT2ATSHRCYP2D6 | |
| Hydrochloric Acid SCHEMBL7768569 | 0.90 | NPC1 (0.46) | MAPTADRB1ADRB3NPC1RAB9A | |
| SCHEMBL7772527 | 0.90 | SMN1; SMN2 (0.47) | MAPTMEN1KMT2ATSHRADRB1 | |
| SCHEMBL7768353 | 0.89 | RAB9A (0.50) | MAPTMEN1KMT2ACYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL7769434 | 0.86 | RAB9A (0.50) | MAPTTSHRCYP2D6CYP2C19CYP1A2 | |
| SCHEMBL7769549 | 0.83 | ADRB2 (0.52) | MEN1KMT2AADRB2ADRB1ADRB3 | |
| SCHEMBL6321815 | 0.78 | MAPT (0.66) | MAPTMEN1KMT2ATSHRCYP2D6 | |
| SCHEMBL6321825 | 0.78 | MAPT (0.66) | MAPTMEN1KMT2ATSHRCYP2D6 | |
| SCHEMBL7770335 | 0.76 | MAPT (0.46) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL9661011 | 0.75 | MAPT (0.78) | MAPTMEN1KMT2ATSHRCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107944-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012462-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-09 | — | — | WO | disclosed |