Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 8/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 8/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7770332 | 0.83 | MAPT (0.54) | ADRB2ADRB1ADRB3NPC1RAB9A | |
| SCHEMBL7770327 | 0.83 | MAPT (0.54) | ADRB2ADRB1ADRB3NPC1RAB9A | |
| SCHEMBL7772527 | 0.83 | SMN1; SMN2 (0.47) | ADRB1ADRB3NPC1HPGDRAB9A | |
| Hydrochloric Acid SCHEMBL7768569 | 0.83 | NPC1 (0.46) | ADRB1ADRB3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7768353 | 0.82 | RAB9A (0.50) | NPC1HPGDRAB9ASMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL7769434 | 0.79 | RAB9A (0.50) | ADRB1ADRB3NPC1HPGDRAB9A | |
| SCHEMBL6322046 | 0.78 | ADRB3 (0.63) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL6322039 | 0.78 | ADRB3 (0.63) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL6321975 | 0.73 | LMNA (0.51) | ADRB2ADRB1ADRB3NPC1AR | |
| SCHEMBL7769550 | 0.72 | PGR (0.45) | ADRB2ADRB1ADRB3NPC1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107944-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012462-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-09 | — | — | WO | disclosed |