Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | LTA4H | P09960 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7770327 | 0.89 | MAPT (0.54) | RAB9ANPC1LTA4HMAPTALDH1A1 | |
| SCHEMBL7770332 | 0.89 | MAPT (0.54) | RAB9ANPC1LTA4HMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL7768569 | 0.88 | NPC1 (0.46) | RAB9ANPC1LTA4HMAPTALDH1A1 | |
| SCHEMBL7772527 | 0.88 | SMN1; SMN2 (0.47) | RAB9ANPC1LTA4HMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL7769434 | 0.87 | RAB9A (0.50) | RAB9ANPC1LTA4HMAPTALDH1A1 | |
| SCHEMBL7769549 | 0.82 | ADRB2 (0.52) | RAB9ANPC1KMT2AMEN1HPGD | |
| SCHEMBL6323886 | 0.79 | ADRB1 (0.53) | RAB9ANPC1MAPTALDH1A1KMT2A | |
| SCHEMBL6323884 | 0.79 | ADRB1 (0.53) | RAB9ANPC1MAPTALDH1A1KMT2A | |
| SCHEMBL7768355 | 0.73 | RAB9A (0.46) | RAB9ANPC1MAPTALDH1A1KMT2A | |
| SCHEMBL7612152 | 0.73 | MEN1 (0.68) | MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107944-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012462-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-09 | — | — | WO | disclosed |