Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7770797 | 0.93 | ALDH1A1 (0.33) | ALDH1A1MRGPRX4MAOBKDM4EMAPK1 | |
| SCHEMBL7770806 | 0.90 | VDR (0.36) | ALDH1A1MRGPRX4MAOBRAB9AALOX5 | |
| SCHEMBL6155690 | 0.79 | LCK (0.38) | ALDH1A1TSHR | |
| SCHEMBL7770803 | 0.79 | ALDH1A1 (0.34) | ALDH1A1MRGPRX4MAOBLMNAL3MBTL1 | |
| SCHEMBL6157330 | 0.70 | VDR (0.50) | MAOBLMNACYP4F2CYP4A11VDR | |
| SCHEMBL6155882 | 0.69 | MAOB (0.46) | MRGPRX4MAOBRAB9AALOX5L3MBTL1 | |
| SCHEMBL7508753 | 0.68 | ALDH1A1 (0.45) | ALDH1A1KDM4ELMNARAB9ASMN1; SMN2 | |
| SCHEMBL3283097 | 0.67 | KAT8 (0.39) | — | |
| SCHEMBL27974805 | 0.66 | ALDH1A1 (0.37) | ALDH1A1MAPK1ALOX5TSHRL3MBTL1 | |
| SCHEMBL6154870 | 0.66 | ALOX5 (0.44) | MAOBALOX5VDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |