SCHEMBL7770822

SCHEMBL7770822

C=CCOC1(c2ccccc2)C=CC=CC1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29106734 0.85 BCHE (0.34)
SCHEMBL30618845 0.78
SCHEMBL30786886 0.77 OPRM1 (0.39) LMNA
SCHEMBL32671788 0.76 THRB (0.47) LMNA
SCHEMBL28770225 0.76 HDAC4 (0.38)
SCHEMBL4099106 0.75 HTR1A (0.30)
SCHEMBL30618852 0.74
SCHEMBL9293875 0.74
SCHEMBL8663513 0.70 LMNA (0.36) LMNAGAA
SCHEMBL22577725 0.67 HDAC4 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1114029-A1 NOVEL COMPOUNDS AstraZeneca AB (SE) 2001-07-11 EP disclosed
WO-2000015614-A1 NOVEL COMPOUNDS ASTRAZENECA AB (SE) 2000-03-23 WO disclosed